CARB-X awards $4.55 million for Pseudomonas antibody treatmentCARB-X, an initiative to build a better pipeline of new antibiotics for treating resistant infections, announced today that it awarded Inhibrx $4.55 million to speed up the development of a new antibody to prevent and treat Pseudomonas, a hard-to-treat Gram-negative pathogen often found in health settings.The award includes the possibility of $1.49 million more if Inhibrx, a biotherapy company based in La Jolla, Calif., meets certain development milestones with INBRX-111, which is currently in preclinical trials.The Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) is a joint effort between the United States and the United Kingdom and is funded by the Biomedical Advanced Research and Development Authority (BARDA) and the Wellcome Trust, with additional support from the National Institute of Allergy and Infectious Diseases (NIAID).Kevin Outterson, JD, executive director of CARB-X, said in a statement from the group that the Inhibrx project enriches the diversity of the CARB-X pipeline. He added that though projects in the CARB-X portfolio are in the early stages of research and come with a high risk of failure. ” But if successful, these projects, including Inhibrx’s antibody project, hold exciting potential in the fight against the deadliest antibiotic-resistant bacteria.”Mark Lappe, chief executive officer of Inhibrx, said company looks forward to advancing INBRX-111 rapidly though phase 1 trials.The new award pushes CARB-X announced funding this year to $51.93 million covering 21 projects, with an additional $63.85 million if the groups meet their milestones. CARB-X said it expects to make further funding announcements later this year.Oct 31 CARB-X press release Study: California hospitals show progress on ASPs following new state law The proportion of California hospitals with all of the Centers for Disease Control and Prevention’s (CDC’s) core elements for antibiotic stewardship rose from 59% to 69% following new state legislation requiring hospitals to implement additional stewardship practices, researchers with the California Department of Public Health reported yesterday in Infection Control and Hospital Epidemiology.To assess implementation of antimicrobial stewardship programs (ASPs) before and after Senate Bill 1311 went into effect in 2015, the researchers analyzed the responses of California hospitals in 2014 and 2015 to an annual survey by the CDC’s National Healthcare Safety Network (NHSN) that included questions about antibiotic stewardship practices. The law required hospitals to institute an antibiotic stewardship policy in accordance with guidelines established by the federal government and professional organizations, to develop a physician-supervised stewardship team with at least one physician or pharmacist who had received stewardship training, and to report all stewardship activities to appropriate hospital committees.In total, 386 of 388 California hospitals completed the surveys in 2014 and 2015. Analysis of the survey answers showed that 267 hospitals (69.2%) had all seven of the CDC’s core elements for hospital ASPs in 2015, compared with 229 (59.3%) in 2014. Nationally, only 48% of hospitals that reported to NHSN in 2015 had ASPs with all seven core elements.The authors say the extent to which the legislation affected hospital ASPs is beyond the scope of the analysis. “However, in combination with recommendations from professional and government organizations, it is likely that this legislation had a catalyzing effect on California’s ASP progress,” they write. Oct 30 Infect Control Hosp Epidemiol studyWelsh deaths from resistant, healthcare-related infections continue declineIn Wales, the number of deaths from the most common antibiotic-resistant and healthcare associated infections such as methicillin-resistant Staphylococcus aureus (MRSA) continued to decline in 2016, the BBC reported today, citing the latest statistics from the country’s Office for National Statistics.According to the results, MRSA deaths reflected a 22-year low; only 10 death certificates in 2016 noted MRSA, lower than the 14 recorded in 1994.For Clostridium difficile, a common healthcare-associated infection that often affects older patients who are on antibiotics for other infections, Wales noted a rise in 2013, but the 79 deaths last year are the lowest since 2001, according to the report. For Staphylococcus aureus, the number of deaths in Wales last was the lowest since 1994.The Welsh government released its Antimicrobial Resistance Delivery Plan in March. A government spokesperson told the BBC that the fall in deaths is a sign of overall progress National Health Service (NHS) Wales is making toward reducing healthcare-associated infections.Oct 31 BBC reportC diff statistics MRSA statistics
Sebagai salah satu perusahaan multi-nasional yang memiliki segudang pengalaman di dunia aviasi global, Airbus melihat kondisi ini sebagai satu keuntungan tersendiri untuk mereka. Dalam pemberitaan sebelumnya, Airbus diketahui tengah merancang sebuah drone otonom yang dimaksudkan sebagai angkutan futuristik. Dengan kondisi seperti yang sudah di jabarkan di atas, mereka memiliki kesempatan untuk merangkul manufaktur otomotif guna melancarkan misi bersama dan mengembangkan pasar drone.Seperti yang diwartakan KabarPenumpang.com dari laman newatlas.com (7/3/2018), Airbus berkolaborasi dengan Audi untuk menghadirkan Pop.Up Next, sebuah moda yang dapat berjalan secara otonom di darat dan juga dapat mengudara. Ini merupakan kembangan dari konsep Pop.Up yang pernah dipamerkan Airbus di Geneva Motor Show pada tahun lalu.Di darat, mobil mini dengan kapasitas dua penumpang ini mampu meluncur hingga mencapai top speed 100 km per jam dengan menggunakan baterai bertenaga 15 kWh untuk jarak tempuh 130 km. Jika anda terjebak macet, Anda cukup memesan salah satu drone milik Airbus yang tersedia di stasiun pengisian daya terdekat melalui aplikasi. Di sana, mobil Pop.Up Next akan diangkut menggunakan drone Airbus dengan teknologi khusus. Ketika sudah bertransformasi menjadi moda udara, Pop.Up Next mampu menempuh jarak 50 km dengan kecepatan 540 km per jam. Keren, bukan?Sumber: newatlas.comDi sini, Audi berperan sebagai ‘motor’ dari Pop.Up Next versi darat. Keahliannya di bidang otomotif tidak lagi diragukan oleh dunia, termasuk bagian interiornya. Berdasarkan peta konsep yang sudah di buat, Pop.Up Next rencananya akan menyematkan sebuah layar berukuran 49 inci yang menggabungkan teknologi eye-tracking dan speech and facial recognition. Penggunaan bahan dasar Pop.Up Next versi darat juga tidak sembarangan. Audi harus menggunakan bahan se-ringan mungkin namun tidak mengesampingkan kekuatannya.Baca Juga: Prototipe Taksi Drone Ehang 184, Sukses Uji Coba Dalam 1000 Kali TerbangSehubungan masih berbentuk konsep dimana potensi perubahan di segala lini masih bisa terjadi, pihak Airbus sendiri mengatakan masih melakukan pertimbangan agar ‘moda dua alam’ ini mampu meningkatkan kinerja dan menekan daya. Kedua belah pihak masih enggan berkomentar mengenai waktu peluncuran dari moda futuristik ini. Jika sudah dipasarkan kelak, apakah Anda berencana untuk memilikinya?Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading… RelatedAudi Pop.Up Next – Terhambat Regulasi, Baru Akan Dirilis 10 Tahun Lagi01/12/2018In “Darat”Tidak Antar Penumpang, Moda Otonom Ini Ditugaskan Untuk Kirim Barang!18/02/2018In “Basis Aplikasi”Audi Pasang Banyak “Mata” Untuk Sistem Auto Pilot di Armada Anyarnya18/09/2017In “Darat” Bukan suatu hal yang baru ketika dewasa ini banyak manufaktur otomotif yang mulai berupaya mencari ceruk usaha lain. Pasalnya, para pengusaha menilai bahwa penjualan mobil konvensional sebentar lagi akan menemui ‘jalan buntu’. Ya, kondisi kemacetan yang semakin tidak bisa ditolerir belakangan ini membuat para pengguna jalan seolah enggan untuk menambah koleksi kendaraan mereka.Baca Juga: Berusaha Tetap di Arus Persaingan, Porsche pun Turut Luncurkan Taksi Udara Otonom!Ketika pemerintah sudah berusaha untuk memperbaiki sistem angkutan umum agar volume kendaraan di jalanan dapat berkurang, namun para pengguna kendaraan pribadi tetap enggan untuk beralih menggunakan moda transportasi berbasis massal tersebut. Walhasil, kemacetan pun semakin meradang.
Erik Sviatchenko has a “good chance” of facing Rangers in Sunday’s Scottish Cup semi-final says Ronny Deila.The Danish defender suffered a thigh injury in last week’s 0-0 draw with Dundee and sat out the weekend win over Motherwell.Sviatchenko has established himself at the heart of Celtic’s defence since arriving in January and Deila believes the 24-year-old will be back in time for the Hampden clash.Deila told Sky Sports News HQ: “He has a good chance. So we will see. It’s too early to say. He has a grade one pulled muscle so it’s a good chance.” Dedryck Boyata didn’t train on Tuesday while Jozo Simunovic is out but Deila feels Boyata will be available in time.The Celtic boss added: “He’ll be fine, it’s just a small thing. Everyone knows what is coming up, it’s just to make themselves ready for Sunday now.”
Donegal Councillor John O’Donnell is to appear before the Standards in Public Office Commission next week for a public hearing on alleged contraventions of the Ethical Framework for Local Government Service. Cllr O’Donnell is one of three Irish Councillors who appeared in an RTE Investigates exposé to be called before SIPO.SIPO announced today that the Letterkenny MD Cllr O’Donnell will face an Investigation Hearing on Tuesday 11st September in Dublin. Cllr John O’Donnell faces allegations of ethical breaches after he was filmed in a meeting with an undercover reporter in the RTÉ Investigates Standards in Public Office programme in December 2015.The documentary showed Cllr O’Donnell telling a reporter posing as a wind farm investor that he wanted to be paid indirectly for lobbying on behalf of the development.Cllr O’Donnell claimed that he had been speaking in his capacity as a businessman and not as a local councillor when the recordings were made.Councillor Hugh McElvaney of Monaghan County Council and Councillor Joe Queenan of Sligo County Council are also facing hearings next week relating to the undercover reports by RTÉ. The hearings will investigate if the politicians breached the ethical framework under the Local Government Act 2001.Cllr John O’Donnell to face investigation hearing before SIPO was last modified: September 6th, 2018 by Staff WriterShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:Cllr John O’DonnellRTE InvestigatesSIPO
Dons play at Spencer on ThursdayBy Paul LeckerSports ReporterMARSHFIELD — Gilman scored 14 times in the second inning and went on to rough up Marshfield Columbus Catholic 24-1 in a Cloverbelt Conference East Division softball game Tuesday at the Marshfield Fairgrounds.The game was shortened to three innings due to Gilman’s big lead.Gilman only had one hit as Dons’ pitchers combined for 22 walks and four hit batters.The Dons (1-4, 0-4 Cloverbelt East) plays at Spencer on Thursday.(Hub City Times Sports Reporter Paul Lecker is also the publisher of MarshfieldAreaSports.com.)Pirates 24, Dons 1Gilman 1(14)9 – 24 1 0Columbus Catholic 100 – 1 3 2WP: Kasee Burton. LP: Maddie DeSmet.SO: Burton 2; DeSmet (1 1/3 inn.) 2, Sierra Litwaitis (1/3 inn.) 0, Addison Baierl (2/3 inn.) 2, Ella Schultz (2/3 inn.) 0. BB: Burton 1; DeSmet 7, Litwaitis 5, Baierl 5, Schultz 5.Top hitters: G, Gunseth 4 runs; Burton 4 runs. CC, Litwaitis 2B.Records: Gilman 5-2, 1-1 Cloverbelt Conference East Divison; Columbus Catholic 1-4, 0-4 Cloverbelt East.
The 49th International Mathematical Olympiad, held in Madrid, Spain, in 2008. (Image: 49th IMO) Intense concentration as a participant solves her maths problem. (Image: 49th IMO)Janine ErasmusSouth Africa is hosting the 19th Pan-African Mathematics Olympiad, an annual event organised by the African Mathematical Union (AMU) that brings together the brightest minds on the continent. The event takes place in Pretoria from 19 to 26 April 2009.Entry into the prestigious competition, which is supported by the national Department of Science and Technology and organised by the South African Mathematics Foundation, is by invitation only. The event is held in both French and English, and the objective is to nurture talent and share information on teaching methods and mathematics curricula across the African continent.In 2009 there will be 13 countries taking part – Niger, Burkina Faso, Senegal, Kenya, Benin, Zimbabwe, Nigeria, Algeria, Uganda, Mali, Mozambique, the Ivory Coast and the hosts, South Africa. Each team consists of a leader who is a mathematics teacher at secondary or tertiary level, and four pupils, all of whom must be younger than 20 years old on the day of the second examination paper, and must not be enrolled in any post-secondary institution.At the end of the event an international jury will award the gold, silver and bronze individual medals as well as the medals for the top three countries. There will also be special prizes and honourable mentions, and every participant will receive a certificate.Encouraging creative thinkingAccording to the Department of Science and Technology, the event will create an environment that will provide opportunities for creative thinking for mathematically inclined minds in the technological environment. The South African government, in partnership with the private sector, is actively looking to boost the country’s international competitiveness in all spheres of technology.South African has participated in the Pan-African Olympiad for a number of years. The country took top honours in 2000 – its début year of participation – as well as in 2002, 2003, 2006, 2007 and 2008, and is hoping to repeat this notable achievement in 2009 with its two teams.These are made up of some of the brightest young mathematical minds in the country. The official team comprises Arlton Gilbert (Star College, Durban), Dessi Nikolov (Eunice High School, Bloemfontein), Greg Jackson (Diocesan College, Cape Town) and Hlanganani Shibambo (Wordsworth High School, Benoni).In the unofficial team are Sean Wentzel (Westerford High School), Kira Düsterwald (Springfield Convent), Charl du Plessis (Stellenberg High School), Ashraf Moolla (Rondebosch Boys’ High School) and Rofhiwa Mauda (Mbilwi Secondary School). With the exception of Mbilwi School in Sibasa, Limpopo province, all pupils in the unofficial team come from schools in Cape Town.In 2008 Thomas Weighill of Paarl Boys’ High School was the top participant overall, and Dessi Nikolov of Eunice High School in Bloemfontein came third, and was also the top girl.The country has fared less spectacularly in the international version of the event, coming in 44th in 2008 and 68th in 2007. South Africa has participated in the International Mathematical Olympiad since 1992 and its best performance came in 2000 when it took 27th place.The origins of mathsEvidence exists to show that mathematics was born in Africa, and mathematicians from the continent are in agreement that Africa has every right to reclaim its place at the global forefront of the discipline.A notched calendar stick over 35 000 years old, discovered recently in the Border cave in the Lebombo mountains in the eastern part of the Southern Africa, is the oldest mathematical artefact known. The stick, known as the Lebombo bone, is a tally stick – a tool on which cuts were made to keep a count or a score – with 29 distinct notches that were deliberately cut into a baboon’s fibula. The ancient artefact resembles the calendar sticks still used by Bushmen in Namibia.The written form of the science also originated in Africa, when the pyramid-builders of ancient Egypt used papyrus to notate their calculations and formulae around 5 000 years ago. And 2 000 years ago in the great Egyptian city of Alexandria, mathematics developed fully into a rigorous axiomatic subject, notably through the efforts of great scholars such as Ptolemy and the Greek mathematician Euclid.Developing maths in AfricaThe African Mathematical Union is the continent’s equivalent of the International Mathematical Union, and is dedicated to the development of mathematics in Africa. Founded in 1976 at the first Pan-African Conference of Mathematicians held in Rabat, Morocco, the AMU was presided over by renowned Cameroonian mathematician and politician Henri Hogbe Nlend until 1986.The AMU’s second president was Nigerian academic Aderemi Kuku who at the time was head of the Department of Mathematics at Ibadan University. The Union set up four commissions in 1986 – the Commission on the History of Mathematics in Africa; the Commission on Women in Mathematics in Africa; the Commission Mathematics Education; and the Commission on Mathematics Olympiad.The third Pan-African Congress of Mathematicians was held in 1991 in Nairobi, Kenya, where Kuku was re-elected and served another presidential term of office. At the fourth congress held in 1995 in Ifrane, Morocco, Ahmed Kerkour, president of the Moroccan Mathematical Society and also of the Al Akhawayn University, was elected AMU president.During the same year the newly democratic South Africa joined the AMU, and the 2000 congress was held in Cape Town. Here South Africa participated for the first time in the Pan-African Mathematics Olympiad.Professor Jan Persens of the University of the Western Cape, South Africa, took over the presidency of the AMU from Kerkour in 2000.Since 1978 the AMU has published the journal Afrika Matematika.Do you have queries or comments about this article? Contact Janine Erasmus at [email protected] articlesTeam SA to debate at model UN Education in South AfricaUseful linksAfrican Mathematical UnionSouth African Mathematics FoundationDepartment of Science and TechnologySouth African Agency for Science and Technology AdvancementAfrika MatematicaMathematicians of the African Diaspora49th International Mathematical Olympiad (Spain)International Mathematical Olympiad
“We just didn’t want to leave our fate in the hands of other teams,” said coach Vergel Meneses as the Bombers entered the Final Four for the fifth time in seven seasons.Tey Teodoro finished with 19 points, before limping off in the last two minutes due to an ankle injury, while Jed Mendoza added 10 points, including a couple of key baskets in the final period that helped put away the Cardinals.The Chiefs refused to let up in the final period even after losing top playmaker Kent Salado due to a knee injury midway in the last quarter.Salado fired 22 points, before leaving the game.“With what happened today, I need to play for us to have a chance in the Final Four,” said Salado.ADVERTISEMENT Sports Related Videospowered by AdSparcRead Next Trump to designate Mexican drug cartels as terrorist groups Jordan delivers on promise: 2 Cobra choppers now in PH Winter storm threatens to scramble Thanksgiving travel plans Argentine bishop appears at court hearing on abuse charges LATEST STORIES NU targets perfect tourney The win improved the Bombers’ record to 11-6, assuring them of third spot at the end of the elimination round.But the Chiefs blew the race for the remaining Final Four spot open after turning back the San Sebastian Stags, 85-79, in the second game.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingWhile Letran still has the inside track for the last postseason berth with an 8-8 record, Arellano’s win forged a tie at fifth spot with San Sebastian at 7-9.Emilio Aguinaldo College remains in contention with a 6-10 record, but the Generals have to win their remaining games while hoping that no other contender goes beyond nine wins. View comments Hotel says PH coach apologized for ‘kikiam for breakfast’ claim MOST READ Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ Don’t miss out on the latest news and information. Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims No more menthol cigarettes: New ban on tobacco, vape flavors Jose Rizal U punched its ticket to the Final Four, while Arellano lived to fight another day as the NCAA Season 93 playoff race took another twist on Tuesday at Filoil Flying V Centre in San Juan.In cruise control for most of the game, the Heavy Bombers avoided complications with a narrow 62-58 victory over the Mapua Cardinals, leaving Letran, Arellano, San Sebastian and Emilio Aguinaldo College to fight it out for the remaining Final Four berth.ADVERTISEMENT
Chelsea have signed Stoke City’s Bosnian international goalkeeper Asmir Begovic on a four-year contract, the Premier League champions confirmed on Monday.The 28-year-old, who joined Stoke from Portsmouth in 2010, has signed for a fee reported in British media to be worth eight million pounds ($12.44 million).Begovic will compete with first-choice Belgium goalkeeper Thibaut Courtois at Stamford Bridge after Petr Cech ended his trophy-laden 11-year spell by joining rivals Arsenal last month.”I am very happy to be joining Chelsea. After speaking at length to the manager (Jose Mourinho), I feel like I can develop here and be an important part of this team,” Begovic told Chelsea’s official website (www.chelseafc.com).Begovic becomes Chelsea’s second signing of the close season after Colombian striker Radamel Falcao joined from AS Monaco on a season-long loan deal.
Greyson Lambert ReadingFormer Georgia wide receiver Malcolm Mitchell went from struggling to read when he began his college career to being inspired to write a children’s book after joining a book club during his time at Georgia. This morning, Georgia quarterback Greyson Lambert read his former teammate’s book, “The Magician’s Hat” to a group of youths at a local summer reading program kickoff. Reading is always a good thing, and Lambert sharing Mitchell’s book with kids is even better.
HALIFAX – Nova Scotia’s government-owned cannabis retailer said it has successfully taken measures to prevent people from skirting the access code required as part of age verification for online sales.The problem popped up hours after the use of cannabis became legal, when someone posted a 77-second online video offering instructions on how to get around using the required access cards.Beverley Ware, spokeswoman for the Nova Scotia Liquor Corporation, said late Thursday afternoon the Crown entity believes it has solved the issue.“It involved moving data stored in a browser to a server,” she said in an email.Earlier, Ware said the change the corporation made “means that you won’t be able to bypass the access code anymore.”She said Nova Scotia is one of two provinces that has a two-step age verification process that involves inputting an access code and then confirming the customer is at least 19 years old.In order to purchase cannabis products online in Nova Scotia, adults have to pick up an access code in person at the province’s liquor and cannabis stores, after showing proof of age. The access code is free and there is no personal information attached to it.Ware said there is an additional step to ensure cannabis is not being purchased by minors.“No matter how you place your order, when it’s shipped to the door the person who receives it still has to provide photo ID proving that they live at that address and proving that they are 19 years old,” Ware said.She said deliveries must be made person-to-person or the product will be shipped back to the corporation.When asked about whether it was possible to know if an adult was getting around the security measures for a minor, Ware raised the idea of social responsibility.“We would hope that Nova Scotians wouldn’t provide liquor to minors and cigarettes to those under age. There is a certain amount of responsibility here that if you are an adult purchasing cannabis we would hope that you don’t provide it to a minor, and it’s illegal to provide it to a minor.”But Nova Scotia’s Opposition Progressive Conservatives said the video was proof that the province’s Liberal government had “failed to keep the drug out of children’s hands.”“They have proven that in addition to not being able to trust them with our private information, we can’t trust them to protect our children,” interim Tory Leader Karla MacFarlane said in a news release.Meanwhile, the liquor corporation said it conducted 12,810 transactions province-wide during the first day of legalization Wednesday, resulting in $660,000 in total sales — with $47,000 of that coming from online sales.